Cargando…
Defining regorafenib as a senomorphic drug: therapeutic potential in the age-related lung disease emphysema
Senescence, a hallmark of aging, is a factor in age-related diseases (ARDs). Therefore, targeting senescence is widely regarded as a practicable method for modulating the effects of aging and ARDs. Here, we report the identification of regorafenib, an inhibitor of multiple receptor tyrosine kinases,...
Autores principales: | Park, Jung-Jin, Oh, Kwangseok, Lee, Gun-Wu, Bang, Geul, Park, Jin-Hee, Kim, Han-Byeol, Kim, Jin Young, Shin, Eun-Young, Kim, Eung-Gook |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167251/ https://www.ncbi.nlm.nih.gov/pubmed/37009796 http://dx.doi.org/10.1038/s12276-023-00966-6 |
Ejemplares similares
-
Regorafenib prevents the development of emphysema in a murine elastase model
por: Oh, Kwangseok, et al.
Publicado: (2023) -
Kinesin-1-dependent transport of the βPIX/GIT complex in neuronal cells
por: Shin, Eun-Young, et al.
Publicado: (2021) -
PAK4 signaling in health and disease: defining the PAK4–CREB axis
por: Won, So-Yoon, et al.
Publicado: (2019) -
The use of regorafenib for patients with refractory metastatic colorectal cancer in clinical practice
por: Yoon, Sang Eun, et al.
Publicado: (2018) -
Senolytic and senomorphic secondary metabolites as therapeutic agents in Drosophila melanogaster models of Parkinson’s disease
por: Miller, Sean J., et al.
Publicado: (2023)