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Prediction of HLA genotypes from single-cell transcriptome data

The human leukocyte antigen (HLA) locus plays a central role in adaptive immune function and has significant clinical implications for tissue transplant compatibility and allelic disease associations. Studies using bulk-cell RNA sequencing have demonstrated that HLA transcription may be regulated in...

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Detalles Bibliográficos
Autores principales:	Solomon, Benjamin D., Zheng, Hong, Dillon, Laura W., Goldman, Jason D., Hourigan, Christopher S., Heath, James R., Khatri, Purvesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167300/ https://www.ncbi.nlm.nih.gov/pubmed/37180102 http://dx.doi.org/10.3389/fimmu.2023.1146826

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