Antibacterial activity of vB_AbaM_PhT2 phage hydrophobic amino acid fusion endolysin, combined with colistin against Acinetobacter baumannii

Phage lytic enzymes are promising antimicrobial agents. In this study, an endolysin derived from vB_AbaM_PhT2 (vPhT2), was identified. This endolysin represented the conserved lysozyme domain. Recombinant endolysin (lysAB- vT2) and hydrophobic fusion endolysin (lysAB-vT2-fusion) were expressed and p...

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Detalles Bibliográficos
Autores principales: Sitthisak, Sutthirat, Manrueang, Suphattra, Khongfak, Supat, Leungtongkam, Udomluk, Thummeepak, Rapee, Thanwisai, Aunchalee, Burton, Nathan, Dhanoa, Gurneet K., Tsapras, Panagiotis, Sagona, Antonia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167329/
https://www.ncbi.nlm.nih.gov/pubmed/37156803
http://dx.doi.org/10.1038/s41598-023-33822-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167329/
https://www.ncbi.nlm.nih.gov/pubmed/37156803
http://dx.doi.org/10.1038/s41598-023-33822-8

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