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Comparison of Group-Level and Individualized Brain Regions for Measuring Change in Longitudinal Tau Positron Emission Tomography in Alzheimer Disease

IMPORTANCE: Longitudinal tau positron emission tomography (PET) is a relevant outcome in clinical trials evaluating disease-modifying therapies in Alzheimer disease (AD). A key unanswered question is whether the use of participant-specific (individualized) regions of interest (ROIs) is superior to c...

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Detalles Bibliográficos
Autores principales:	Leuzy, Antoine, Binette, Alexa Pichet, Vogel, Jacob W., Klein, Gregory, Borroni, Edilio, Tonietto, Matteo, Strandberg, Olof, Mattsson-Carlgren, Niklas, Palmqvist, Sebastian, Pontecorvo, Michael J., Iaccarino, Leonardo, Stomrud, Erik, Ossenkoppele, Rik, Smith, Ruben, Hansson, Oskar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167602/ https://www.ncbi.nlm.nih.gov/pubmed/37155176 http://dx.doi.org/10.1001/jamaneurol.2023.1067

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