Nivolumab‐induced fatal myocarditis: A case report

KEY CLINICAL MESSAGE: Baseline assessment and interval monitoring with a careful history, clinical examination, laboratory work‐up, and noninvasive imaging modalities may be beneficial for early detection of immune checkpoint inhibitor‐associated side effects. ABSTRACT: Previous reports of immune ch...

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Autores principales: Bharathidasan, Kavya, Abdelnabi, Mahmoud, Abdelmalek, John, Sekhon, Jasmine, Butler, William, Quirch, Miguel, Sosa, Erwin Argueta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167613/
https://www.ncbi.nlm.nih.gov/pubmed/37180331
http://dx.doi.org/10.1002/ccr3.7306
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author Bharathidasan, Kavya
Abdelnabi, Mahmoud
Abdelmalek, John
Sekhon, Jasmine
Butler, William
Quirch, Miguel
Sosa, Erwin Argueta
author_facet Bharathidasan, Kavya
Abdelnabi, Mahmoud
Abdelmalek, John
Sekhon, Jasmine
Butler, William
Quirch, Miguel
Sosa, Erwin Argueta
author_sort Bharathidasan, Kavya
collection PubMed
description KEY CLINICAL MESSAGE: Baseline assessment and interval monitoring with a careful history, clinical examination, laboratory work‐up, and noninvasive imaging modalities may be beneficial for early detection of immune checkpoint inhibitor‐associated side effects. ABSTRACT: Previous reports of immune checkpoint inhibitors' cardiotoxic effects include pericarditis, myocarditis, myocardial infarction, ventricular dysfunction, vasculitis, and electrical abnormalities. The authors report a case of acute heart failure caused by nivolumab‐induced cardiotoxicity in a middle‐aged man with advanced esophageal carcinoma with no previous cardiac history or significant cardiovascular risk factors.
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spelling pubmed-101676132023-05-10 Nivolumab‐induced fatal myocarditis: A case report Bharathidasan, Kavya Abdelnabi, Mahmoud Abdelmalek, John Sekhon, Jasmine Butler, William Quirch, Miguel Sosa, Erwin Argueta Clin Case Rep Case Report KEY CLINICAL MESSAGE: Baseline assessment and interval monitoring with a careful history, clinical examination, laboratory work‐up, and noninvasive imaging modalities may be beneficial for early detection of immune checkpoint inhibitor‐associated side effects. ABSTRACT: Previous reports of immune checkpoint inhibitors' cardiotoxic effects include pericarditis, myocarditis, myocardial infarction, ventricular dysfunction, vasculitis, and electrical abnormalities. The authors report a case of acute heart failure caused by nivolumab‐induced cardiotoxicity in a middle‐aged man with advanced esophageal carcinoma with no previous cardiac history or significant cardiovascular risk factors. John Wiley and Sons Inc. 2023-05-09 /pmc/articles/PMC10167613/ /pubmed/37180331 http://dx.doi.org/10.1002/ccr3.7306 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bharathidasan, Kavya
Abdelnabi, Mahmoud
Abdelmalek, John
Sekhon, Jasmine
Butler, William
Quirch, Miguel
Sosa, Erwin Argueta
Nivolumab‐induced fatal myocarditis: A case report
title Nivolumab‐induced fatal myocarditis: A case report
title_full Nivolumab‐induced fatal myocarditis: A case report
title_fullStr Nivolumab‐induced fatal myocarditis: A case report
title_full_unstemmed Nivolumab‐induced fatal myocarditis: A case report
title_short Nivolumab‐induced fatal myocarditis: A case report
title_sort nivolumab‐induced fatal myocarditis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167613/
https://www.ncbi.nlm.nih.gov/pubmed/37180331
http://dx.doi.org/10.1002/ccr3.7306
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