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Photochemical Wolff Rearrangement Initiated Generation and Subsequent α-Chlorination of C1 Ammonium Enolates

[Image: see text] The enantioselective synthesis of α-chlorinated carboxylic acid esters with er up to 99:1 and yields up to 82% was achieved via a one-pot multistep protocol starting from α-diazoketones. This process proceeds via a photochemical Wolff rearrangement, trapping of the generated ketene...

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Detalles Bibliográficos
Autores principales:	Weinzierl, David, Piringer, Magdalena, Zebrowski, Paul, Stockhammer, Lotte, Waser, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167681/ https://www.ncbi.nlm.nih.gov/pubmed/37098273 http://dx.doi.org/10.1021/acs.orglett.3c00986

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