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HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()

Infectious diseases, such as Black Death, Spanish Flu, and COVID-19, have accompanied human history and threatened public health, resulting in enormous infections and even deaths among citizens. Because of their rapid development and huge impact, laying out interventions becomes one of the most crit...

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Detalles Bibliográficos
Autores principales: Du, Xinqi, Chen, Hechang, Yang, Bo, Long, Cheng, Zhao, Songwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167779/
https://www.ncbi.nlm.nih.gov/pubmed/37193062
http://dx.doi.org/10.1016/j.ins.2023.119065
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author Du, Xinqi
Chen, Hechang
Yang, Bo
Long, Cheng
Zhao, Songwei
author_facet Du, Xinqi
Chen, Hechang
Yang, Bo
Long, Cheng
Zhao, Songwei
author_sort Du, Xinqi
collection PubMed
description Infectious diseases, such as Black Death, Spanish Flu, and COVID-19, have accompanied human history and threatened public health, resulting in enormous infections and even deaths among citizens. Because of their rapid development and huge impact, laying out interventions becomes one of the most critical paths for policymakers to respond to the epidemic. However, the existing studies mainly focus on epidemic control with a single intervention, which makes the epidemic control effectiveness severely compromised. In view of this, we propose a Hierarchical Reinforcement Learning decision framework for multi-mode Epidemic Control with multiple interventions called HRL4EC. We devise an epidemiological model, referred to as MID-SEIR, to describe multiple interventions' impact on transmission explicitly, and use it as the environment for HRL4EC. Besides, to address the complexity introduced by multiple interventions, this work transforms the multi-mode intervention decision problem into a multi-level control problem, and employs hierarchical reinforcement learning to find the optimal strategies. Finally, extensive experiments are conducted with real and simulated epidemic data to validate the effectiveness of our proposed method. We further analyze the experiment data in-depth, conclude a series of findings on epidemic intervention strategies, and make a visualization accordingly, which can provide heuristic support for policymakers' pandemic response.
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spelling pubmed-101677792023-05-10 HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control() Du, Xinqi Chen, Hechang Yang, Bo Long, Cheng Zhao, Songwei Inf Sci (N Y) Article Infectious diseases, such as Black Death, Spanish Flu, and COVID-19, have accompanied human history and threatened public health, resulting in enormous infections and even deaths among citizens. Because of their rapid development and huge impact, laying out interventions becomes one of the most critical paths for policymakers to respond to the epidemic. However, the existing studies mainly focus on epidemic control with a single intervention, which makes the epidemic control effectiveness severely compromised. In view of this, we propose a Hierarchical Reinforcement Learning decision framework for multi-mode Epidemic Control with multiple interventions called HRL4EC. We devise an epidemiological model, referred to as MID-SEIR, to describe multiple interventions' impact on transmission explicitly, and use it as the environment for HRL4EC. Besides, to address the complexity introduced by multiple interventions, this work transforms the multi-mode intervention decision problem into a multi-level control problem, and employs hierarchical reinforcement learning to find the optimal strategies. Finally, extensive experiments are conducted with real and simulated epidemic data to validate the effectiveness of our proposed method. We further analyze the experiment data in-depth, conclude a series of findings on epidemic intervention strategies, and make a visualization accordingly, which can provide heuristic support for policymakers' pandemic response. Elsevier Inc. 2023-09 2023-05-09 /pmc/articles/PMC10167779/ /pubmed/37193062 http://dx.doi.org/10.1016/j.ins.2023.119065 Text en © 2023 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Du, Xinqi
Chen, Hechang
Yang, Bo
Long, Cheng
Zhao, Songwei
HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()
title HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()
title_full HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()
title_fullStr HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()
title_full_unstemmed HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()
title_short HRL4EC: Hierarchical reinforcement learning for multi-mode epidemic control()
title_sort hrl4ec: hierarchical reinforcement learning for multi-mode epidemic control()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167779/
https://www.ncbi.nlm.nih.gov/pubmed/37193062
http://dx.doi.org/10.1016/j.ins.2023.119065
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