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Different regulatory mechanisms of the capsule in hypervirulent Klebsiella pneumonia: “direct” wcaJ variation vs. “indirect” rmpA regulation

INTRODUCTION: Hypervirulent Klebsiella pneumoniae produce an increased amount of capsular substance and are associated with a hypermucoviscous phenotype. Capsule production is regulated by capsular regulatory genes and capsular gene cluster variations. In the present study, we focus on the effect of...

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Detalles Bibliográficos
Autores principales: Wang, Weiwen, Tian, Dongxing, Hu, Dakang, Chen, Wenjie, Zhou, Ying, Jiang, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168181/
https://www.ncbi.nlm.nih.gov/pubmed/37180440
http://dx.doi.org/10.3389/fcimb.2023.1108818