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Uncovering the hidden structure of dynamic T cell composition in peripheral blood during cancer immunotherapy: a topic modeling approach

Immune checkpoint inhibitors (ICIs), now mainstays in the treatment of cancer treatment, show great potential but only benefit a subset of patients. A more complete understanding of the immunological mechanisms and pharmacodynamics of ICI in cancer patients will help identify the patients most likel...

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Detalles Bibliográficos
Autores principales: Peng, Xiyu, Lee, Jasme, Adamow, Matthew, Maher, Colleen, Postow, Michael A., Callahan, Margaret K., Panageas, Katherine S., Shen, Ronglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168231/
https://www.ncbi.nlm.nih.gov/pubmed/37162890
http://dx.doi.org/10.1101/2023.04.24.538095