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Human V-ATPase a-subunit isoforms bind specifically to distinct phosphoinositide phospholipids
V-ATPases are highly conserved multi-subunit enzymes that maintain the distinct pH of eukaryotic organelles. The integral membrane a-subunit is encoded by tissue and organelle specific isoforms, and its cytosolic N-terminal domain (aNT) modulates organelle specific regulation and targeting of V-ATPa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168244/ https://www.ncbi.nlm.nih.gov/pubmed/37162989 http://dx.doi.org/10.1101/2023.04.24.538068 |