3D structural human interactome reveals proteome-wide perturbations by disease mutations

Human genome sequencing studies have identified numerous loci associated with complex diseases. However, translating human genetic and genomic findings to disease pathobiology and therapeutic discovery remains a major challenge at multiscale interactome network levels. Here, we present a deep-learni...

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Detalles Bibliográficos
Autores principales: Xiong, Dapeng, Zhao, Junfei, Qiu, Yunguang, Zhou, Yadi, Lee, Dongjin, Gupta, Shobhita, Lu, Weiqiang, Liang, Siqi, Kang, Jin Joo, Eng, Charis, Loscalzo, Joseph, Cheng, Feixiong, Yu, Haiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168245/
https://www.ncbi.nlm.nih.gov/pubmed/37162909
http://dx.doi.org/10.1101/2023.04.24.538110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168245/
https://www.ncbi.nlm.nih.gov/pubmed/37162909
http://dx.doi.org/10.1101/2023.04.24.538110

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