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A mechanism that integrates microtubule motors of opposite polarity at the kinetochore corona

Chromosome biorientation on the mitotic spindle is prerequisite to errorless genome inheritance. CENP-E (kinesin 7) and Dynein-Dynactin (DD), microtubule motors with opposite polarity, promote biorientation from the kinetochore corona, a polymeric structure whose assembly requires MPS1 kinase. The c...

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Detalles Bibliográficos
Autores principales:	Cmentowski, Verena, Ciossani, Giuseppe, d’Amico, Ennio, Wohlgemuth, Sabine, Owa, Mikito, Dynlacht, Brian, Musacchio, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168246/ https://www.ncbi.nlm.nih.gov/pubmed/37163019 http://dx.doi.org/10.1101/2023.04.25.538277

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