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Unveiling the Domain-Specific and RAS Isoform-Specific Details of BRAF Regulation
BRAF is a key member in the MAPK signaling pathway essential for cell growth, proliferation, and differentiation. Dysregulation or mutation of BRAF is often the underlying cause of various types of cancer. RAS, a small GTPase protein that acts upstream of BRAF, has been identified as a driver of up...
Autores principales: | Trebino, Tarah, Markusic, Borna, Nan, Haihan, Banerjee, Shrhea, Wang, Zhihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168249/ https://www.ncbi.nlm.nih.gov/pubmed/37163002 http://dx.doi.org/10.1101/2023.04.24.538112 |
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