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Unveiling the Domain-Specific and RAS Isoform-Specific Details of BRAF Regulation

BRAF is a key member in the MAPK signaling pathway essential for cell growth, proliferation, and differentiation. Dysregulation or mutation of BRAF is often the underlying cause of various types of cancer. RAS, a small GTPase protein that acts upstream of BRAF, has been identified as a driver of up...

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Detalles Bibliográficos
Autores principales: Trebino, Tarah, Markusic, Borna, Nan, Haihan, Banerjee, Shrhea, Wang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168249/
https://www.ncbi.nlm.nih.gov/pubmed/37163002
http://dx.doi.org/10.1101/2023.04.24.538112

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