Cell based dATP delivery as a therapy for chronic heart failure

Transplanted human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) improve ventricular performance when delivered acutely post-myocardial infarction but are ineffective in chronic myocardial infarction/heart failure. 2’-deoxy-ATP (dATP) activates cardiac myosin and potently increases contrac...

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Detalles Bibliográficos
Autores principales: Mhatre, Ketaki N, Mathieu, Julie, Martinson, Amy, Flint, Galina, Blakley, Leslie P, Tabesh, Arash, Reinecke, Hans, Yang, Xiulan, Guan, Xuan, Murali, Eesha, Klaiman, Jordan M, Odom, Guy L, Brown, Mary Beth, Tian, Rong, Hauschka, Stephen D, Raftery, Daniel, Moussavi-Harami, Farid, Regnier, Michael, Murry, Charles E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168250/
https://www.ncbi.nlm.nih.gov/pubmed/37162854
http://dx.doi.org/10.1101/2023.04.24.538108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168250/
https://www.ncbi.nlm.nih.gov/pubmed/37162854
http://dx.doi.org/10.1101/2023.04.24.538108

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