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Supporting-cell vs. hair-cell survival in the human cochlea: Implications for regenerative therapies

Animal studies have shown that the supporting-cells surviving in the organ of Corti after cochlear insult can be transdifferentiated into hair cells as a treatment for sensorineural hearing loss. Clinical trials of small-molecule therapeutics have been undertaken, but little is known about how to pr...

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Detalles Bibliográficos
Autores principales: Kaur, Charanjeet, Van Orden, McKayla, O’Malley, Jennifer T., Wu, Pei-zhe, Liberman, M. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168255/
https://www.ncbi.nlm.nih.gov/pubmed/37163013
http://dx.doi.org/10.1101/2023.04.24.538119