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Supporting-cell vs. hair-cell survival in the human cochlea: Implications for regenerative therapies
Animal studies have shown that the supporting-cells surviving in the organ of Corti after cochlear insult can be transdifferentiated into hair cells as a treatment for sensorineural hearing loss. Clinical trials of small-molecule therapeutics have been undertaken, but little is known about how to pr...
Autores principales: | Kaur, Charanjeet, Van Orden, McKayla, O’Malley, Jennifer T., Wu, Pei-zhe, Liberman, M. Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168255/ https://www.ncbi.nlm.nih.gov/pubmed/37163013 http://dx.doi.org/10.1101/2023.04.24.538119 |
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