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Competition between transcription and loop extrusion modulates promoter and enhancer dynamics
The spatiotemporal configuration of genes with distal regulatory elements, and the impact of chromatin mobility on transcription, remain unclear. Loop extrusion is an attractive model for bringing genetic elements together, but how this functionally interacts with transcription is also largely unkno...
Autores principales: | Platania, Angeliki, Erb, Cathie, Barbieri, Mariano, Molcrette, Bastien, Grandgirard, Erwan, de Kort, Marit AC, Meaburn, Karen, Taylor, Tiegh, Shchuka, Virlana M, Kocanova, Silvia, Oliveira, Guilherme Monteiro, Mitchell, Jennifer A, Soutoglou, Evi, Lenstra, Tineke L, Molina, Nacho, Papantonis, Argyris, Bystricky, Kerstin, Sexton, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168261/ https://www.ncbi.nlm.nih.gov/pubmed/37162887 http://dx.doi.org/10.1101/2023.04.25.538222 |
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