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Competition between transcription and loop extrusion modulates promoter and enhancer dynamics

The spatiotemporal configuration of genes with distal regulatory elements, and the impact of chromatin mobility on transcription, remain unclear. Loop extrusion is an attractive model for bringing genetic elements together, but how this functionally interacts with transcription is also largely unkno...

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Detalles Bibliográficos
Autores principales: Platania, Angeliki, Erb, Cathie, Barbieri, Mariano, Molcrette, Bastien, Grandgirard, Erwan, de Kort, Marit AC, Meaburn, Karen, Taylor, Tiegh, Shchuka, Virlana M, Kocanova, Silvia, Oliveira, Guilherme Monteiro, Mitchell, Jennifer A, Soutoglou, Evi, Lenstra, Tineke L, Molina, Nacho, Papantonis, Argyris, Bystricky, Kerstin, Sexton, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168261/
https://www.ncbi.nlm.nih.gov/pubmed/37162887
http://dx.doi.org/10.1101/2023.04.25.538222