Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues

The ability to sense and respond to proteotoxic insults declines with age, leaving cells vulnerable to chronic and acute stressors. Reproductive cues modulate this decline in cellular proteostasis to influence organismal stress resilience in C. elegans. We previously uncovered a pathway that links t...

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Detalles Bibliográficos
Autores principales: Sala, Ambre J., Grant, Rogan A., Imran, Ghania, Morton, Claire, Brielmann, Renee M., Bott, Laura C., Watts, Jennifer, Morimoto, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168274/
https://www.ncbi.nlm.nih.gov/pubmed/37162952
http://dx.doi.org/10.1101/2023.04.25.537803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168274/
https://www.ncbi.nlm.nih.gov/pubmed/37162952
http://dx.doi.org/10.1101/2023.04.25.537803

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