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TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis

Nuclear pore complexes (NPCs) regulate information transfer between the nucleus and cytoplasm. NPC defects are linked to several neurological diseases, but the processes governing NPC biogenesis and spatial organization are poorly understood. Here, we identify a temporal window of strongly upregulat...

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Detalles Bibliográficos
Autores principales:	Kim, Sumin, Phan, Sébastien, Shaw, Thomas R., Ellisman, Mark H., Veatch, Sarah L., Barmada, Sami J., Pappas, Samuel S., Dauer, William T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168336/ https://www.ncbi.nlm.nih.gov/pubmed/37162852 http://dx.doi.org/10.1101/2023.04.26.538491

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