HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model

The central nervous system (CNS) is a major human immunodeficiency virus type 1 reservoir. Microglia are the primary target cell of HIV-1 infection in the CNS. Current models have not allowed the precise molecular pathways of acute and chronic CNS microglial infection to be tested with in vivo genet...

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Detalles Bibliográficos
Autores principales: Min, Alice K., Javidfar, Behnam, Missall, Roy, Doanman, Donald, Durens, Madel, Vil, Samantha St, Masih, Zahra, Graziani, Mara, Mordelt, Annika, Marro, Samuele, de Witte, Lotje, Chen, Benjamin K., Swartz, Talia H., Akbarian, Schahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168358/
https://www.ncbi.nlm.nih.gov/pubmed/37162838
http://dx.doi.org/10.1101/2023.04.26.538461

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