Cargando…

Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis

Meiotic DNA double-strand breaks (DSBs) initiate homologous recombination and are crucial for ensuring proper chromosome segregation. In mice, ANKRD31 recently emerged as a regulator of DSB timing, number, and location, with a particularly important role in targeting DSBs to the pseudoautosomal regi...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jiaqi, Li, Tao, Kim, Coojong, Boekhout, Michiel, Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168363/
https://www.ncbi.nlm.nih.gov/pubmed/37162821
http://dx.doi.org/10.1101/2023.04.27.538541