CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions

The sheer complexity of the brain has complicated our ability to understand its cellular mechanisms in health and disease. Genome-wide association studies have uncovered genetic variants associated with specific neurological phenotypes and diseases. In addition, single-cell transcriptomics have prov...

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Detalles Bibliográficos
Autores principales: Li, Emmy, Benitez, Camila, Boggess, Steven C., Koontz, Mark, Rose, Indigo V.L., Draeger, Nina, Teter, Olivia M., Samelson, Avi J., Ullian, Erik M., Kampmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168378/
https://www.ncbi.nlm.nih.gov/pubmed/37163077
http://dx.doi.org/10.1101/2023.04.26.538498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168378/
https://www.ncbi.nlm.nih.gov/pubmed/37163077
http://dx.doi.org/10.1101/2023.04.26.538498

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