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CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
The sheer complexity of the brain has complicated our ability to understand its cellular mechanisms in health and disease. Genome-wide association studies have uncovered genetic variants associated with specific neurological phenotypes and diseases. In addition, single-cell transcriptomics have prov...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168378/ https://www.ncbi.nlm.nih.gov/pubmed/37163077 http://dx.doi.org/10.1101/2023.04.26.538498 |