The mitochondrial Ca(2+) channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation

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The mitochondrial uniporter (MCU) Ca(2+) ion channel represents the primary means for Ca(2+) uptake into mitochondria. Here we employed in vitro and in vivo models with MCU genetically eliminated to understand how MCU contributes to tumor formation and progression. Transformation of primary fibrobla...

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Detalles Bibliográficos
Autores principales: García, Emily Fernández, Paudel, Usha, Noji, Michael C., Bowman, Caitlyn E., Pitarresi, Jason R., Rustgi, Anil K., Wellen, Kathryn E., Arany, Zolt, Weissenrieder, Jillian S., Foskett, J. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168388/
https://www.ncbi.nlm.nih.gov/pubmed/37163088
http://dx.doi.org/10.1101/2023.04.26.538295
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