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A single-cell atlas of the aging murine ovary

Ovarian aging leads to diminished fertility, dysregulated endocrine signaling, and increased chronic disease burden. These effects begin to emerge long before follicular exhaustion. Around 35 years old, women experience a sharp decline in fertility, corresponding to declines in oocyte quality. Despi...

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Detalles Bibliográficos
Autores principales: Isola, José V. V., Ocañas, Sarah R., Hubbart, Chase R., Ko, Sunghwan, Mondal, Samim Ali, Hense, Jessica D., Carter, Hannah N. C., Schneider, Augusto, Kovats, Susan, Alberola-Ila, José, Freeman, Willard M., Stout, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168416/
https://www.ncbi.nlm.nih.gov/pubmed/37162983
http://dx.doi.org/10.1101/2023.04.29.538828