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A single-cell atlas of the aging murine ovary
Ovarian aging leads to diminished fertility, dysregulated endocrine signaling, and increased chronic disease burden. These effects begin to emerge long before follicular exhaustion. Around 35 years old, women experience a sharp decline in fertility, corresponding to declines in oocyte quality. Despi...
Autores principales: | Isola, José V. V., Ocañas, Sarah R., Hubbart, Chase R., Ko, Sunghwan, Mondal, Samim Ali, Hense, Jessica D., Carter, Hannah N. C., Schneider, Augusto, Kovats, Susan, Alberola-Ila, José, Freeman, Willard M., Stout, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168416/ https://www.ncbi.nlm.nih.gov/pubmed/37162983 http://dx.doi.org/10.1101/2023.04.29.538828 |
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