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Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage
CRISPR-Cas systems are an adaptive immune system in bacteria and archaea that utilize CRISPR RNA-guided surveillance complexes to target complementary RNA or DNA for destruction(1–5). Target RNA cleavage at regular intervals is characteristic of type III effector complexes; however, the mechanism ha...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168453/ https://www.ncbi.nlm.nih.gov/pubmed/37163044 http://dx.doi.org/10.21203/rs.3.rs-2837968/v1 |