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Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage

CRISPR-Cas systems are an adaptive immune system in bacteria and archaea that utilize CRISPR RNA-guided surveillance complexes to target complementary RNA or DNA for destruction(1–5). Target RNA cleavage at regular intervals is characteristic of type III effector complexes; however, the mechanism ha...

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Detalles Bibliográficos
Autores principales: Schwartz, Evan A., Bravo, Jack P.K., Ahsan, Mohd, Macias, Luis A., McCafferty, Caitlyn L., Dangerfield, Tyler L., Walker, Jada N., Brodbelt, Jennifer S., Palermo, Giulia, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168453/
https://www.ncbi.nlm.nih.gov/pubmed/37163044
http://dx.doi.org/10.21203/rs.3.rs-2837968/v1

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