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Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage
CRISPR-Cas systems are an adaptive immune system in bacteria and archaea that utilize CRISPR RNA-guided surveillance complexes to target complementary RNA or DNA for destruction(1–5). Target RNA cleavage at regular intervals is characteristic of type III effector complexes; however, the mechanism ha...
Autores principales: | Schwartz, Evan A., Bravo, Jack P.K., Ahsan, Mohd, Macias, Luis A., McCafferty, Caitlyn L., Dangerfield, Tyler L., Walker, Jada N., Brodbelt, Jennifer S., Palermo, Giulia, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168453/ https://www.ncbi.nlm.nih.gov/pubmed/37163044 http://dx.doi.org/10.21203/rs.3.rs-2837968/v1 |
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