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Identifying Quantitatively Differential Chromosomal Compartmentalization Changes and Their Biological Significance from Hi-C data using DARIC

BACKGROUND: Chromosomal compartmentalization plays a critical role in maintaining proper transcriptional programs in cell differentiation and oncogenesis. However, currently the prevalent method for comparative analysis of compartmentalization landscapes between different cell types is limited to th...

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Detalles Bibliográficos
Autores principales: Kai, Yan, Liu, Nan, Orkin, Stuart H, Yuan, Guo-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168473/
https://www.ncbi.nlm.nih.gov/pubmed/37162846
http://dx.doi.org/10.21203/rs.3.rs-2814806/v1