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Identifying Quantitatively Differential Chromosomal Compartmentalization Changes and Their Biological Significance from Hi-C data using DARIC
BACKGROUND: Chromosomal compartmentalization plays a critical role in maintaining proper transcriptional programs in cell differentiation and oncogenesis. However, currently the prevalent method for comparative analysis of compartmentalization landscapes between different cell types is limited to th...
Autores principales: | Kai, Yan, Liu, Nan, Orkin, Stuart H, Yuan, Guo-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168473/ https://www.ncbi.nlm.nih.gov/pubmed/37162846 http://dx.doi.org/10.21203/rs.3.rs-2814806/v1 |
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