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Mechanisms underlying the antiarrhythmic effect of ARumenamide-787 in experimental models of the J wave syndromes and hypothermia

BACKGROUND: Brugada (BrS) and early repolarization syndromes (ERS), the so-called J wave syndromes (JWS), are associated with life-threatening ventricular arrhythmias. Pharmacologic approaches to therapy are currently limited. In this study, we examine the effects of ARumenamide-787 (AR-787) to supp...

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Detalles Bibliográficos
Autores principales:	Di Diego, José M., Barajas-Martinez, Hector, Cox, Robert, Robinson, Victoria M., Jung, Joseph, Fouda, Mohamed, Abdelsayed, Mena, Ruben, Peter C., Antzelevitch, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168548/ https://www.ncbi.nlm.nih.gov/pubmed/37159454 http://dx.doi.org/10.1371/journal.pone.0281977

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