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matchRanges: generating null hypothesis genomic ranges via covariate-matched sampling

MOTIVATION: Deriving biological insights from genomic data commonly requires comparing attributes of selected genomic loci to a null set of loci. The selection of this null set is non-trivial, as it requires careful consideration of potential covariates, a problem that is exacerbated by the non-unif...

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Detalles Bibliográficos
Autores principales: Davis, Eric S, Mu, Wancen, Lee, Stuart, Dozmorov, Mikhail G, Love, Michael I, Phanstiel, Douglas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168584/
https://www.ncbi.nlm.nih.gov/pubmed/37084270
http://dx.doi.org/10.1093/bioinformatics/btad197

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