Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band

Motor symptoms of Parkinson’s Disease (PD) are associated with dopamine deficits and pathological oscillation of basal ganglia (BG) neurons in the β range ([12-30] Hz). However, how dopamine depletion affects the oscillation dynamics of BG nuclei is still unclear. With a spiking neurons model, we he...

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Detalles Bibliográficos
Autores principales: Ortone, Andrea, Vergani, Alberto Arturo, Ahmadipour, Mahboubeh, Mannella, Riccardo, Mazzoni, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168586/
https://www.ncbi.nlm.nih.gov/pubmed/37104542
http://dx.doi.org/10.1371/journal.pcbi.1010645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168586/
https://www.ncbi.nlm.nih.gov/pubmed/37104542
http://dx.doi.org/10.1371/journal.pcbi.1010645

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