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Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band
Motor symptoms of Parkinson’s Disease (PD) are associated with dopamine deficits and pathological oscillation of basal ganglia (BG) neurons in the β range ([12-30] Hz). However, how dopamine depletion affects the oscillation dynamics of BG nuclei is still unclear. With a spiking neurons model, we he...
Autores principales: | Ortone, Andrea, Vergani, Alberto Arturo, Ahmadipour, Mahboubeh, Mannella, Riccardo, Mazzoni, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168586/ https://www.ncbi.nlm.nih.gov/pubmed/37104542 http://dx.doi.org/10.1371/journal.pcbi.1010645 |
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