PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1

Polycomb repressive complex 2 (PRC2) mediates H3K27me3 deposition, which is thought to recruit canonical PRC1 (cPRC1) via chromodomain-containing CBX proteins to promote stable repression of developmental genes. PRC2 forms two major subcomplexes, PRC2.1 and PRC2.2, but their specific roles remain un...

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Detalles Bibliográficos
Autores principales: Glancy, Eleanor, Wang, Cheng, Tuck, Ellen, Healy, Evan, Amato, Simona, Neikes, Hannah K., Mariani, Andrea, Mucha, Marlena, Vermeulen, Michiel, Pasini, Diego, Bracken, Adrian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168607/
https://www.ncbi.nlm.nih.gov/pubmed/37030288
http://dx.doi.org/10.1016/j.molcel.2023.03.018

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