Structure of the Reductase Domain of a Fungal Carboxylic Acid Reductase and Its Substrate Scope in Thioester and Aldehyde Reduction

[Image: see text] The synthesis of aldehydes from carboxylic acids has long been a challenge in chemistry. In contrast to the harsh chemically driven reduction, enzymes such as carboxylic acid reductases (CARs) are considered appealing biocatalysts for aldehyde production. Although structures of sin...

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Detalles Bibliográficos
Autores principales: Daniel, Bastian, Hashem, Chiam, Leithold, Marlene, Sagmeister, Theo, Tripp, Adrian, Stolterfoht-Stock, Holly, Messenlehner, Julia, Keegan, Ronan, Winkler, Christoph K., Ling, Jonathan Guyang, Younes, Sabry H.H., Oberdorfer, Gustav, Abu Bakar, Farah Diba, Gruber, Karl, Pavkov-Keller, Tea, Winkler, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168641/
https://www.ncbi.nlm.nih.gov/pubmed/37180375
http://dx.doi.org/10.1021/acscatal.2c04426

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