Protocol, rationale and design of BE-PEOPLE (Bedaquiline enhanced exposure prophylaxis for LEprosy in the Comoros): a cluster randomized trial on effectiveness of rifampicin and bedaquiline as post-exposure prophylaxis of leprosy contacts

BACKGROUND: Leprosy is an ancient infectious disease with an annual global incidence of around 200,000 over the past decade. Since 2018, the World Health Organization (WHO) recommends single-dose rifampicin as post-exposure prophylaxis (SDR-PEP) for contacts of leprosy patients. The Post ExpOsure Pr...

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Detalles Bibliográficos
Autores principales: Younoussa, Assoumani, Samidine, Said Nourdine, Bergeman, Auke T., Piubello, Alberto, Attoumani, Nissad, Grillone, Silahi Halifa, Braet, Sofie Marijke, Tsoumanis, Achilleas, Baco, Abdallah, Mzembaba, Aboubacar, Salim, Zahara, Amidy, Mohamed, Grillone, Saverio, Snijders, Rian, Corstjens, Paul, Ortuno-Gutierrez, Nimer, Hoof, Carolien, Geluk, Annemieke, de Jong, Bouke C., Hasker, Epco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169125/
https://www.ncbi.nlm.nih.gov/pubmed/37161571
http://dx.doi.org/10.1186/s12879-023-08290-0

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