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Role of phytocompounds as the potential anti-viral agent: an overview

Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines’ developments remain uncanny. In this century of the biological era, human viruses act predominantly as vers...

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Autores principales: Mohanty, Swati Sucharita, Sahoo, Chita Ranjan, Paidesetty, Sudhir Kumar, Padhy, Rabindra Nath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169142/
https://www.ncbi.nlm.nih.gov/pubmed/37160482
http://dx.doi.org/10.1007/s00210-023-02517-2
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author Mohanty, Swati Sucharita
Sahoo, Chita Ranjan
Paidesetty, Sudhir Kumar
Padhy, Rabindra Nath
author_facet Mohanty, Swati Sucharita
Sahoo, Chita Ranjan
Paidesetty, Sudhir Kumar
Padhy, Rabindra Nath
author_sort Mohanty, Swati Sucharita
collection PubMed
description Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines’ developments remain uncanny. In this century of the biological era, human viruses act predominantly as versatile spreaders. The infection of the present COVID-19 virus is up in the air; blithely, the integument of medicinal chemistry approaches, particularly bioactive derived phytocompounds could be helpful to control those human viruses, recognized in the last 100 years. Indeed, natural products are being used for various therapeutic purposes. The major bioactive phytocompounds are chemically containing coumarin, thiosulfonate, steroid, polysaccharide, tannin, lignin, proanthocyanidin, terpene, quinone, saponin, flavonoid, alkaloid, and polyphenol, that are documented for inhibitory action against several viral infections. Mostly, about 20–30% of plants from tropical or temperate regions are known to have some antiviral activity. This comprehensive analysis of bioactive-derived phytocompounds would represent a significant impact and might be helpful for antiviral research and the current state of viral treatments.
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spelling pubmed-101691422023-05-11 Role of phytocompounds as the potential anti-viral agent: an overview Mohanty, Swati Sucharita Sahoo, Chita Ranjan Paidesetty, Sudhir Kumar Padhy, Rabindra Nath Naunyn Schmiedebergs Arch Pharmacol Review Viral diseases are the most notorious infective agent(s) causing morbidity and mortality in every nook and corner for ages; viruses are active in host cells, and specific anti-virus medicines’ developments remain uncanny. In this century of the biological era, human viruses act predominantly as versatile spreaders. The infection of the present COVID-19 virus is up in the air; blithely, the integument of medicinal chemistry approaches, particularly bioactive derived phytocompounds could be helpful to control those human viruses, recognized in the last 100 years. Indeed, natural products are being used for various therapeutic purposes. The major bioactive phytocompounds are chemically containing coumarin, thiosulfonate, steroid, polysaccharide, tannin, lignin, proanthocyanidin, terpene, quinone, saponin, flavonoid, alkaloid, and polyphenol, that are documented for inhibitory action against several viral infections. Mostly, about 20–30% of plants from tropical or temperate regions are known to have some antiviral activity. This comprehensive analysis of bioactive-derived phytocompounds would represent a significant impact and might be helpful for antiviral research and the current state of viral treatments. Springer Berlin Heidelberg 2023-05-09 /pmc/articles/PMC10169142/ /pubmed/37160482 http://dx.doi.org/10.1007/s00210-023-02517-2 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Mohanty, Swati Sucharita
Sahoo, Chita Ranjan
Paidesetty, Sudhir Kumar
Padhy, Rabindra Nath
Role of phytocompounds as the potential anti-viral agent: an overview
title Role of phytocompounds as the potential anti-viral agent: an overview
title_full Role of phytocompounds as the potential anti-viral agent: an overview
title_fullStr Role of phytocompounds as the potential anti-viral agent: an overview
title_full_unstemmed Role of phytocompounds as the potential anti-viral agent: an overview
title_short Role of phytocompounds as the potential anti-viral agent: an overview
title_sort role of phytocompounds as the potential anti-viral agent: an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169142/
https://www.ncbi.nlm.nih.gov/pubmed/37160482
http://dx.doi.org/10.1007/s00210-023-02517-2
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