A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4(+) cell distribution in the human rectal mucosa

To reduce HIV transmission, locally applied pre-exposure prophylaxis (PrEP) products for anorectal use will be important complements to oral and injectable PrEP products already available. It is critical to preserve an intact rectal epithelium and avoid an influx of mucosal HIV target cells with suc...

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Detalles Bibliográficos
Autores principales: Franzén Boger, Mathias, Benhach, Nora, Hasselrot, Tyra, Brand, Rhonda M., Rohan, Lisa C., Wang, Lin, McGowan, Ian, Edick, Stacey, Ho, Ken, Meyn, Leslie, Matoba, Nobuyuki, Palmer, Kenneth E., Broliden, Kristina, Tjernlund, Annelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169179/
https://www.ncbi.nlm.nih.gov/pubmed/37161022
http://dx.doi.org/10.1038/s41598-023-34107-w

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