A role for lipophagy in atherosclerosis

Lipophagy is a type of selective autophagy that targets lipid droplets for degradation. Since the discovery of lipophagy in 2009, research has uncovered a central role for this process in cellular lipid metabolism, including in atherogenic foam cells. Therefore, increasing lipophagy might be a thera...

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Detalles Bibliográficos
Autores principales: Laval, Thomas, Ouimet, Mireille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169197/
https://www.ncbi.nlm.nih.gov/pubmed/37161064
http://dx.doi.org/10.1038/s41569-023-00885-z
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author Laval, Thomas
Ouimet, Mireille
author_facet Laval, Thomas
Ouimet, Mireille
author_sort Laval, Thomas
collection PubMed
description Lipophagy is a type of selective autophagy that targets lipid droplets for degradation. Since the discovery of lipophagy in 2009, research has uncovered a central role for this process in cellular lipid metabolism, including in atherogenic foam cells. Therefore, increasing lipophagy might be a therapeutic target to reverse lipid build-up in atherosclerosis.
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spelling pubmed-101691972023-05-11 A role for lipophagy in atherosclerosis Laval, Thomas Ouimet, Mireille Nat Rev Cardiol Comment Lipophagy is a type of selective autophagy that targets lipid droplets for degradation. Since the discovery of lipophagy in 2009, research has uncovered a central role for this process in cellular lipid metabolism, including in atherogenic foam cells. Therefore, increasing lipophagy might be a therapeutic target to reverse lipid build-up in atherosclerosis. Nature Publishing Group UK 2023-05-09 /pmc/articles/PMC10169197/ /pubmed/37161064 http://dx.doi.org/10.1038/s41569-023-00885-z Text en © Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Laval, Thomas
Ouimet, Mireille
A role for lipophagy in atherosclerosis
title A role for lipophagy in atherosclerosis
title_full A role for lipophagy in atherosclerosis
title_fullStr A role for lipophagy in atherosclerosis
title_full_unstemmed A role for lipophagy in atherosclerosis
title_short A role for lipophagy in atherosclerosis
title_sort role for lipophagy in atherosclerosis
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169197/
https://www.ncbi.nlm.nih.gov/pubmed/37161064
http://dx.doi.org/10.1038/s41569-023-00885-z
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