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Gastric cancer cell-originated small extracellular vesicle induces metabolic reprogramming of BM-MSCs through ERK-PPARγ-CPT1A signaling to potentiate lymphatic metastasis

Tumor microenvironment and metabolic reprogramming are critical for tumor metastasis. Bone marrow-derived mesenchymal stem cells (BM-MSCs) are widely involved in the formation of tumor microenvironment and present oncogenic phenotypes to facilitate lymph node metastasis (LNM) in response to small ex...

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Detalles Bibliográficos
Autores principales:	Huang, Jiaying, Wang, Xiang, Wen, Jing, Zhao, Xinxin, Wu, Chen, Wang, Lin, Cao, Xiaoli, Dong, Haibo, Xu, Xuejing, Huang, Feng, Zhu, Wei, Wang, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169337/ https://www.ncbi.nlm.nih.gov/pubmed/37158903 http://dx.doi.org/10.1186/s12935-023-02935-5

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