The role of noncoding RNAs in metabolic reprogramming of cancer cells

Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread. It has been discovered that noncoding RNAs (ncRNAs), including microRNA (miRNA), long noncoding RNA (lncRNA), and circula...

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Autores principales: Safi, Amir, Saberiyan, Mohammadreza, Sanaei, Mohammad-Javad, Adelian, Samaneh, Davarani Asl, Fateme, Zeinaly, Mahsa, Shamsi, Mahdi, Ahmadi, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169341/
https://www.ncbi.nlm.nih.gov/pubmed/37161350
http://dx.doi.org/10.1186/s11658-023-00447-8
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author Safi, Amir
Saberiyan, Mohammadreza
Sanaei, Mohammad-Javad
Adelian, Samaneh
Davarani Asl, Fateme
Zeinaly, Mahsa
Shamsi, Mahdi
Ahmadi, Reza
author_facet Safi, Amir
Saberiyan, Mohammadreza
Sanaei, Mohammad-Javad
Adelian, Samaneh
Davarani Asl, Fateme
Zeinaly, Mahsa
Shamsi, Mahdi
Ahmadi, Reza
author_sort Safi, Amir
collection PubMed
description Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread. It has been discovered that noncoding RNAs (ncRNAs), including microRNA (miRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA), have a role in a variety of biological functions, control physiologic and developmental processes, and even influence disease. They have been recognized in numerous cancer types as tumor suppressors and oncogenic agents. The role of ncRNAs in the metabolic reprogramming of cancer cells has recently been noticed. We examine this subject, with an emphasis on the metabolism of glucose, lipids, and amino acids, and highlight the therapeutic use of targeting ncRNAs in cancer treatment.
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spelling pubmed-101693412023-05-11 The role of noncoding RNAs in metabolic reprogramming of cancer cells Safi, Amir Saberiyan, Mohammadreza Sanaei, Mohammad-Javad Adelian, Samaneh Davarani Asl, Fateme Zeinaly, Mahsa Shamsi, Mahdi Ahmadi, Reza Cell Mol Biol Lett Review Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread. It has been discovered that noncoding RNAs (ncRNAs), including microRNA (miRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA), have a role in a variety of biological functions, control physiologic and developmental processes, and even influence disease. They have been recognized in numerous cancer types as tumor suppressors and oncogenic agents. The role of ncRNAs in the metabolic reprogramming of cancer cells has recently been noticed. We examine this subject, with an emphasis on the metabolism of glucose, lipids, and amino acids, and highlight the therapeutic use of targeting ncRNAs in cancer treatment. BioMed Central 2023-05-09 /pmc/articles/PMC10169341/ /pubmed/37161350 http://dx.doi.org/10.1186/s11658-023-00447-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Safi, Amir
Saberiyan, Mohammadreza
Sanaei, Mohammad-Javad
Adelian, Samaneh
Davarani Asl, Fateme
Zeinaly, Mahsa
Shamsi, Mahdi
Ahmadi, Reza
The role of noncoding RNAs in metabolic reprogramming of cancer cells
title The role of noncoding RNAs in metabolic reprogramming of cancer cells
title_full The role of noncoding RNAs in metabolic reprogramming of cancer cells
title_fullStr The role of noncoding RNAs in metabolic reprogramming of cancer cells
title_full_unstemmed The role of noncoding RNAs in metabolic reprogramming of cancer cells
title_short The role of noncoding RNAs in metabolic reprogramming of cancer cells
title_sort role of noncoding rnas in metabolic reprogramming of cancer cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169341/
https://www.ncbi.nlm.nih.gov/pubmed/37161350
http://dx.doi.org/10.1186/s11658-023-00447-8
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