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ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics

Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by NOTCH3 mutations. Typical CADASIL is characterised by subcortical ischemic strokes due to severe arteriopathy and fibrotic thickening of small arteries. Arteriolar vascular smooth muscle...

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Detalles Bibliográficos
Autores principales: Panahi, Mahmod, Hase, Yoshiki, Gallart-Palau, Xavier, Mitra, Sumonto, Watanabe, Atsushi, Low, Roger C, Yamamoto, Yumi, Sepulveda-Falla, Diego, Hainsworth, Atticus H, Ihara, Masafumi, Sze, Siu Kwan, Viitanen, Matti, Behbahani, Homira, Kalaria, Raj N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169505/
https://www.ncbi.nlm.nih.gov/pubmed/37158955
http://dx.doi.org/10.1186/s40478-023-01558-1