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Natural compounds ursolic acid and digoxin exhibit inhibitory activities to cancer cells in RORγ-dependent and -independent manner

Natural compounds ursolic acid (UA) and digoxin isolated from fruits and other plants display potent anti-cancer effects in preclinical studies. UA and digoxin have been at clinical trials for treatment of different cancers including prostate cancer, pancreatic cancer and breast cancer. However, the...

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Detalles Bibliográficos
Autores principales: Zou, Hongye, Yang, Yatian, Chen, Hong-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169565/
https://www.ncbi.nlm.nih.gov/pubmed/37180705
http://dx.doi.org/10.3389/fphar.2023.1146741