Cargando…
Natural compounds ursolic acid and digoxin exhibit inhibitory activities to cancer cells in RORγ-dependent and -independent manner
Natural compounds ursolic acid (UA) and digoxin isolated from fruits and other plants display potent anti-cancer effects in preclinical studies. UA and digoxin have been at clinical trials for treatment of different cancers including prostate cancer, pancreatic cancer and breast cancer. However, the...
Autores principales: | Zou, Hongye, Yang, Yatian, Chen, Hong-Wu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169565/ https://www.ncbi.nlm.nih.gov/pubmed/37180705 http://dx.doi.org/10.3389/fphar.2023.1146741 |
Ejemplares similares
-
Digoxin, an Overlooked Agonist of RORγ/RORγT
por: Karaś, Kaja, et al.
Publicado: (2019) -
Nanoformulations of Ursolic Acid: A Modern Natural Anticancer Molecule
por: Wang, Longyun, et al.
Publicado: (2021) -
The Dichotomous Nature of AZ5104 (an EGFR Inhibitor) Towards RORγ and RORγT
por: Karaś, Kaja, et al.
Publicado: (2019) -
Assessing the Selectivity of FXR, LXRs, CAR, and RORγ Pharmaceutical Ligands With Reporter Cell Lines
por: Toporova, Lucia, et al.
Publicado: (2020) -
Interaction between Chinese medicine and digoxin: Clinical and research update
por: Zhuang, Wei, et al.
Publicado: (2023)