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Monkeypox: a global health emergency
Over the past 2 years, the world has faced the impactful Coronavirus Disease-2019 (COVID-19) pandemic, with a visible shift in economy, medicine, and beyond. As of recent times, the emergence of the monkeypox (mpox) virus infections and the growing number of infected cases have raised panic and fear...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169603/ https://www.ncbi.nlm.nih.gov/pubmed/37180247 http://dx.doi.org/10.3389/fmicb.2023.1094794 |
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author | Stilpeanu, Ruxandra Ilinca Stercu, Ana Maria Stancu, Andreea Lucia Tanca, Antoanela Bucur, Octavian |
author_facet | Stilpeanu, Ruxandra Ilinca Stercu, Ana Maria Stancu, Andreea Lucia Tanca, Antoanela Bucur, Octavian |
author_sort | Stilpeanu, Ruxandra Ilinca |
collection | PubMed |
description | Over the past 2 years, the world has faced the impactful Coronavirus Disease-2019 (COVID-19) pandemic, with a visible shift in economy, medicine, and beyond. As of recent times, the emergence of the monkeypox (mpox) virus infections and the growing number of infected cases have raised panic and fear among people, not only due to its resemblance to the now eradicated smallpox virus, but also because another potential pandemic could have catastrophic consequences, globally. However, studies of the smallpox virus performed in the past and wisdom gained from the COVID-19 pandemic are the two most helpful tools for humanity that can prevent major outbreaks of the mpox virus, thus warding off another pandemic. Because smallpox and mpox are part of the same virus genus, the Orthopoxvirus genus, the structure and pathogenesis, as well as the transmission of both these two viruses are highly similar. Because of these similarities, antivirals and vaccines approved and licensed in the past for the smallpox virus are effective and could successfully treat and prevent an mpox virus infection. This review discusses the main components that outline this current global health issue raised by the mpox virus, by presenting it as a whole, and integrating aspects such as its structure, pathogenesis, clinical aspects, prevention, and treatment options, and how this ongoing phenomenon is being globally approached. |
format | Online Article Text |
id | pubmed-10169603 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101696032023-05-11 Monkeypox: a global health emergency Stilpeanu, Ruxandra Ilinca Stercu, Ana Maria Stancu, Andreea Lucia Tanca, Antoanela Bucur, Octavian Front Microbiol Microbiology Over the past 2 years, the world has faced the impactful Coronavirus Disease-2019 (COVID-19) pandemic, with a visible shift in economy, medicine, and beyond. As of recent times, the emergence of the monkeypox (mpox) virus infections and the growing number of infected cases have raised panic and fear among people, not only due to its resemblance to the now eradicated smallpox virus, but also because another potential pandemic could have catastrophic consequences, globally. However, studies of the smallpox virus performed in the past and wisdom gained from the COVID-19 pandemic are the two most helpful tools for humanity that can prevent major outbreaks of the mpox virus, thus warding off another pandemic. Because smallpox and mpox are part of the same virus genus, the Orthopoxvirus genus, the structure and pathogenesis, as well as the transmission of both these two viruses are highly similar. Because of these similarities, antivirals and vaccines approved and licensed in the past for the smallpox virus are effective and could successfully treat and prevent an mpox virus infection. This review discusses the main components that outline this current global health issue raised by the mpox virus, by presenting it as a whole, and integrating aspects such as its structure, pathogenesis, clinical aspects, prevention, and treatment options, and how this ongoing phenomenon is being globally approached. Frontiers Media S.A. 2023-04-26 /pmc/articles/PMC10169603/ /pubmed/37180247 http://dx.doi.org/10.3389/fmicb.2023.1094794 Text en Copyright © 2023 Stilpeanu, Stercu, Stancu, Tanca and Bucur. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Stilpeanu, Ruxandra Ilinca Stercu, Ana Maria Stancu, Andreea Lucia Tanca, Antoanela Bucur, Octavian Monkeypox: a global health emergency |
title | Monkeypox: a global health emergency |
title_full | Monkeypox: a global health emergency |
title_fullStr | Monkeypox: a global health emergency |
title_full_unstemmed | Monkeypox: a global health emergency |
title_short | Monkeypox: a global health emergency |
title_sort | monkeypox: a global health emergency |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169603/ https://www.ncbi.nlm.nih.gov/pubmed/37180247 http://dx.doi.org/10.3389/fmicb.2023.1094794 |
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