Cargando…

Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking

Detalles Bibliográficos
Autores principales:	Weichenhan, Dieter, Riedel, Anna, Meinen, Charlotte, Basic, Alisa, Toth, Reka, Bähr, Marion, Lutsik, Pavlo, Hey, Joschka, Sollier, Etienne, Toprak, Umut H., Kelekçi, Simge, Lin, Yu-Yu, Hakobyan, Mariam, Touzart, Aurore, Goyal, Ashish, Wierzbinska, Justyna A., Schlesner, Matthias, Westermann, Frank, Lipka, Daniel B., Plass, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169647/ https://www.ncbi.nlm.nih.gov/pubmed/36949154 http://dx.doi.org/10.1038/s41375-023-01865-5

Ejemplares similares

S120: MNX1-ACTIVATING ENHANCER HIJACKING EVENTS IN ACUTE MYELOID LEUKEMIA WITH DELETIONS ON CHROMOSOME 7Q
por: Riedel, Anna, et al.
Publicado: (2023)

PB1808: EPIGENETIC INHIBITOR SCREEN TO IDENTIFY THERAPEUTIC CANDIDATES FOR MNX1-OVEREXPRESSING AML
por: Kelekci, Simge, et al.
Publicado: (2023)

P440: ENHANCER HIJACKING IN COMPLEX-KARYOTYPE AML
por: Sollier, Etienne, et al.
Publicado: (2023)

Club cells employ regeneration mechanisms during lung tumorigenesis
por: Chen, Yuanyuan, et al.
Publicado: (2022)

Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease
por: Hey, Joschka, et al.
Publicado: (2021)

TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3’ neo-enhancer
por: Smith, Charlotte, et al.
Publicado: (2023)

Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands
por: Haller, Florian, et al.
Publicado: (2019)

P416: DNA METHYLATION-BASED CHARACTERIZATION OF ACUTE MYELOID LEUKEMIA POINTS TOWARDS KDM3B AS A 5Q HAPLOINSUFFICIENCY CANDIDATE
por: Kelly, Katherine, et al.
Publicado: (2023)

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone
por: Lutsik, Pavlo, et al.
Publicado: (2020)

ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition
por: Bakr, Ali, et al.
Publicado: (2021)

LncRNA MNX1-AS1 promotes progression of intrahepatic cholangiocarcinoma through the MNX1/Hippo axis
por: Li, Fengwei, et al.
Publicado: (2020)

Neuronal ensemble-specific DNA methylation strengthens engram stability
por: Gulmez Karaca, Kubra, et al.
Publicado: (2020)

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis
por: Souren, Nicole Y., et al.
Publicado: (2019)

MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer
por: Cheng, Yue, et al.
Publicado: (2019)

Systematic evaluation of cell-type deconvolution pipelines for sequencing-based bulk DNA methylomes
por: Jeong, Yunhee, et al.
Publicado: (2022)

Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma
por: Goeppert, Benjamin, et al.
Publicado: (2019)

Dietary Intake patterns in women with GDM and Non-GDM: A comparative study
por: Nadeem, Shabnam, et al.
Publicado: (2022)

Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response
por: Liu, Chun-Shan, et al.
Publicado: (2021)

Expression, Clinical Significance, and Functional Prediction of MNX1 in Breast Cancer
por: Tian, Tian, et al.
Publicado: (2018)

Development and initial testing of a GDM information website for multi-ethnic women with GDM
por: Carolan-Olah, Mary, et al.
Publicado: (2015)

Interactive effect of prepregnancy overweight/obesity and GDM history on prevalence of GDM in biparous women
por: Xu, Xia, et al.
Publicado: (2023)

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL
por: Wierzbinska, Justyna A., et al.
Publicado: (2020)

Gestationsdiabetes (GDM) (Update 2023)
por: Kautzky-Willer, Alexandra, et al.
Publicado: (2023)

Biogenic manganese oxide nanoparticle formation by a multimeric multicopper oxidase Mnx
por: Romano, Christine A., et al.
Publicado: (2017)

Novel MNX1 mutations and genotype–phenotype analysis of patients with Currarino syndrome
por: Han, Lu, et al.
Publicado: (2020)

Perceived Barriers to Management of Gestational Diabetes Mellitus (GDM) and Recommendations for Developing a Mobile App for GDM
por: Bhattarai, Sanju, et al.
Publicado: (2022)

GDM-complicated pregnancies: focus on adipokines
por: Mallardo, Marta, et al.
Publicado: (2021)

Zebrafish Mnx proteins specify one motoneuron subtype and suppress acquisition of interneuron characteristics
por: Seredick, Steve D, et al.
Publicado: (2012)

Pressure dependence of electronic structure and superconductivity of the MnX (X = N, P, As, Sb)
por: Chong, XiaoYu, et al.
Publicado: (2016)

MNX1 reduces sensitivity to anoikis by activating TrkB in human glioma cells
por: Jiang, Lai, et al.
Publicado: (2018)

Pan-Cancer Analysis Identifies MNX1 and Associated Antisense Transcripts as Biomarkers for Cancer
por: Ragusa, Denise, et al.
Publicado: (2022)

Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish
por: Arkhipova, Valeriya, et al.
Publicado: (2012)

Currarino triad with Müllerian duct anomaly in mother and daughter without MNX1 gene mutation
por: Kim, Soo-Hong, et al.
Publicado: (2016)

Spectrum of MNX1 Pathogenic Variants and Associated Clinical Features in Korean Patients with Currarino Syndrome
por: Lee, Seungjun, et al.
Publicado: (2018)

Expression and significance of LncRNA MNX1-AS1 in non-small cell lung cancer
por: Liu, Gaofeng, et al.
Publicado: (2019)

MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34
por: Wu, Junhua, et al.
Publicado: (2023)

Targeted and untargeted metabolomic approach for GDM diagnosis
por: Burzynska-Pedziwiatr, Izabela, et al.
Publicado: (2023)

Comparisons of the oxidative stress biomarkers levels in gestational diabetes mellitus (GDM) and non-GDM among Thai population: cohort study
por: Rueangdetnarong, Hathairat, et al.
Publicado: (2018)

Crk gets hijacked
por: Van Epps, Heather L.
Publicado: (2005)

Hijacking translation in addiction
por: Izquierdo, Alicia, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3o35465lt3qnni8b9k10luvqpa