Distinct oncogenic phenotypes in hematopoietic specific deletions of Trp53

Loss of function in the tumor suppressor gene TP53 is the most common alteration seen in human cancer. In mice, P53 deletion in all cells leads predominantly to the development of T-cell lymphomas, followed by B-cell lymphomas, sarcomas and teratomas. In order to dissect the role of P53 in the hemat...

Descripción completa

Detalles Bibliográficos
Autores principales: Palanichamy, Jayanth Kumar, Tran, Tiffany M., King, Jennifer K., Katzman, Sol, Ritter, Alexander J., Sharma, Gunjan, Tso, Christine, Contreras, Jorge R., Fernando, Thilini R., Sanford, Jeremy R., Rao, Dinesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169790/
https://www.ncbi.nlm.nih.gov/pubmed/37160922
http://dx.doi.org/10.1038/s41598-023-33949-8

Ejemplares similares

Ejemplares similares