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Structural basis for activation of CB1 by an endocannabinoid analog
Endocannabinoids (eCBs) are endogenous ligands of the cannabinoid receptor 1 (CB1), a G protein-coupled receptor that regulates a number of therapeutically relevant physiological responses. Hence, understanding the structural and functional consequences of eCB-CB1 interactions has important implicat...
Autores principales: | Krishna Kumar, Kaavya, Robertson, Michael J., Thadhani, Elina, Wang, Haoqing, Suomivuori, Carl-Mikael, Powers, Alexander S., Ji, Lipin, Nikas, Spyros P., Dror, Ron O., Inoue, Asuka, Makriyannis, Alexandros, Skiniotis, Georgios, Kobilka, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169858/ https://www.ncbi.nlm.nih.gov/pubmed/37160876 http://dx.doi.org/10.1038/s41467-023-37864-4 |
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